Steroid Conversion Calculator
Conversion Result
mg = mg
Daily total: mg/day
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About Steroid Dose Conversions
Our steroid conversion calculator provides clinically-relevant equivalent doses between different glucocorticoids based on their relative anti-inflammatory potency. This tool helps healthcare professionals and patients understand how to safely switch between prednisone, hydrocortisone, dexamethasone, and other corticosteroids while maintaining equivalent therapeutic effects.
Glucocorticoid Equivalent Dose Chart
| Steroid | Equivalent Dose (mg) | Relative Potency | Duration of Action |
|---|---|---|---|
| Hydrocortisone (Cortisol) | 20 | 1 | 8-12 hours |
| Cortisone | 25 | 0.8 | 8-12 hours |
| Prednisone | 5 | 4 | 12-36 hours |
| Prednisolone | 5 | 4 | 12-36 hours |
| Methylprednisolone (Medrol) | 4 | 5 | 12-36 hours |
| Dexamethasone | 0.75 | 30 | 36-72 hours |
Clinical Considerations for Steroid Conversion:
- • Potency varies - Anti-inflammatory effects differ from mineralocorticoid activity
- • Duration matters - Dexamethasone lasts longer than hydrocortisone despite equivalent anti-inflammatory doses
- • Conversion nuances - Prednisone requires hepatic conversion to prednisolone for activity
- • Adrenal suppression - Higher potency steroids cause more HPA axis suppression
- • Dosing schedules - Hydrocortisone often requires 2-3 daily doses due to short duration
- • Patient factors - Hepatic/renal function, age, and comorbidities affect steroid metabolism
Frequently Asked Questions
How do you convert 10mg prednisone to hydrocortisone?
Using our steroid conversion calculator, 10mg prednisone equals approximately 40mg hydrocortisone. This is because prednisone is 4 times more potent than hydrocortisone (20mg hydrocortisone = 5mg prednisone).
What is 4mg methylprednisolone equivalent to in dexamethasone?
4mg methylprednisolone converts to about 0.6mg dexamethasone. Methylprednisolone is 5 times more potent than hydrocortisone, while dexamethasone is 30 times more potent.
Why are steroid conversions important?
Accurate steroid conversions prevent under- or over-dosing when switching medications. Improper conversions can lead to adrenal insufficiency or Cushingoid side effects.